ero1a protein (Danio rerio) - STRING interaction network

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ero1a

ERO1-like protein alpha; Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the folding of immunoglobulins (By similarity). Belongs to the EROs family. (489 aa)

Predicted Functional Partners:

p4hb

0.989

pdia6

0.974

txndc5

0.973

pdia4

0.972

ero1b

0.934

pdia2

0.895

erp44

0.895

txndc16

0.869

pdia7

0.842

pdia3

0.842

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ero1a	ero1b	ENSDARP00000015478	ENSDARP00000139494	ERO1-like protein alpha; Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the folding of immunoglobulins (By similarity). Belongs to the EROs family.	Endoplasmic reticulum oxidoreductase beta.	0.934
ero1a	erp44	ENSDARP00000015478	ENSDARP00000017258	ERO1-like protein alpha; Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the folding of immunoglobulins (By similarity). Belongs to the EROs family.	Thioredoxin domain containing 4 (Endoplasmic reticulum).	0.895
ero1a	p4hb	ENSDARP00000015478	ENSDARP00000138657	ERO1-like protein alpha; Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the folding of immunoglobulins (By similarity). Belongs to the EROs family.	Protein disulfide-isomerase.	0.989
ero1a	pdia2	ENSDARP00000015478	ENSDARP00000012585	ERO1-like protein alpha; Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the folding of immunoglobulins (By similarity). Belongs to the EROs family.	Protein disulfide-isomerase.	0.895
ero1a	pdia3	ENSDARP00000015478	ENSDARP00000134643	ERO1-like protein alpha; Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the folding of immunoglobulins (By similarity). Belongs to the EROs family.	Protein disulfide-isomerase.	0.842
ero1a	pdia4	ENSDARP00000015478	ENSDARP00000018458	ERO1-like protein alpha; Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the folding of immunoglobulins (By similarity). Belongs to the EROs family.	Protein disulfide-isomerase A4; Belongs to the protein disulfide isomerase family.	0.972
ero1a	pdia6	ENSDARP00000015478	ENSDARP00000027662	ERO1-like protein alpha; Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the folding of immunoglobulins (By similarity). Belongs to the EROs family.	Protein disulfide isomerase family A, member 6; Belongs to the protein disulfide isomerase family.	0.974
ero1a	pdia7	ENSDARP00000015478	ENSDARP00000023877	ERO1-like protein alpha; Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the folding of immunoglobulins (By similarity). Belongs to the EROs family.	Protein disulfide-isomerase.	0.842
ero1a	txndc16	ENSDARP00000015478	ENSDARP00000095835	ERO1-like protein alpha; Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the folding of immunoglobulins (By similarity). Belongs to the EROs family.	Thioredoxin domain-containing 16.	0.869
ero1a	txndc5	ENSDARP00000015478	ENSDARP00000116609	ERO1-like protein alpha; Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the folding of immunoglobulins (By similarity). Belongs to the EROs family.	Thioredoxin domain-containing 5; Belongs to the protein disulfide isomerase family.	0.973
ero1b	ero1a	ENSDARP00000139494	ENSDARP00000015478	Endoplasmic reticulum oxidoreductase beta.	ERO1-like protein alpha; Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the folding of immunoglobulins (By similarity). Belongs to the EROs family.	0.934
ero1b	erp44	ENSDARP00000139494	ENSDARP00000017258	Endoplasmic reticulum oxidoreductase beta.	Thioredoxin domain containing 4 (Endoplasmic reticulum).	0.849
ero1b	p4hb	ENSDARP00000139494	ENSDARP00000138657	Endoplasmic reticulum oxidoreductase beta.	Protein disulfide-isomerase.	0.977
ero1b	pdia2	ENSDARP00000139494	ENSDARP00000012585	Endoplasmic reticulum oxidoreductase beta.	Protein disulfide-isomerase.	0.895
ero1b	pdia3	ENSDARP00000139494	ENSDARP00000134643	Endoplasmic reticulum oxidoreductase beta.	Protein disulfide-isomerase.	0.842
ero1b	pdia4	ENSDARP00000139494	ENSDARP00000018458	Endoplasmic reticulum oxidoreductase beta.	Protein disulfide-isomerase A4; Belongs to the protein disulfide isomerase family.	0.983
ero1b	pdia6	ENSDARP00000139494	ENSDARP00000027662	Endoplasmic reticulum oxidoreductase beta.	Protein disulfide isomerase family A, member 6; Belongs to the protein disulfide isomerase family.	0.966
ero1b	pdia7	ENSDARP00000139494	ENSDARP00000023877	Endoplasmic reticulum oxidoreductase beta.	Protein disulfide-isomerase.	0.842
ero1b	txndc16	ENSDARP00000139494	ENSDARP00000095835	Endoplasmic reticulum oxidoreductase beta.	Thioredoxin domain-containing 16.	0.555
ero1b	txndc5	ENSDARP00000139494	ENSDARP00000116609	Endoplasmic reticulum oxidoreductase beta.	Thioredoxin domain-containing 5; Belongs to the protein disulfide isomerase family.	0.965

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