STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
stat1aSignal transducer and activator of transcription. (749 aa)    
Predicted Functional Partners:
irf9
Interferon regulatory factor 9.
   
 0.998
jak1
Tyrosine-protein kinase JAK1; Tyrosine kinase of the non-receptor type. Appears to be required in early development for specific cell migrations (epiboly), expression of homeobox protein goosecoid and formation of anterior structures.
   
 0.996
tyk2
Tyrosine-protein kinase.
   
 0.994
stat2
Signal transducer and activator of transcription.
  
 
0.981
jak2a
Tyrosine-protein kinase.
   
 0.979
jak2b
Tyrosine-protein kinase.
   
 0.974
stat3
Signal transducer and activator of transcription.
  
 
0.945
ikbke
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
   
 0.941
ifnphi1
Interferon phi 1.
     
 0.934
jak3
Tyrosine-protein kinase.
   
 0.931
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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