STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
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[Homology]
Score
sars1Serine--tRNA ligase, cytoplasmic; Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end of tRNA(Ser). Is probably also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec). In the nucleus, binds to the vegfa core promoter and prevents myc binding and transcriptional activation by myc. Thereby inhibits the production of vegfa and sprouting angiogenesis mediated by vegfa. Belongs t [...] (515 aa)    
Predicted Functional Partners:
yars1
Tyrosine--tRNA ligase, cytoplasmic; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
  
  
 0.990
PSTK
Uncharacterized protein.
     
 0.989
wars
Tryptophanyl-tRNA synthetase.
  
 
 0.985
LOC101884223
Uncharacterized protein.
     
 0.983
Wars1
Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.976
mettl6
Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family.
    
 
 0.971
eprs1
Glutamyl-prolyl-tRNA synthetase.
  
 
 0.953
yars2
Tyrosine--tRNA ligase.
  
  
 0.949
gars1
Glycyl-tRNA synthetase.
   
  
 0.949
wars2
Tryptophanyl tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.948
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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