Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dipk2aaDivergent protein kinase domain 2Aa. (432 aa)    
Predicted Functional Partners:
pikfyve
Phosphatidylinositol phosphate 5-kinase type III isoform d.
    
 0.862
vac14
Protein VAC14 homolog; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Acts as a positive activator of PIKfyve kinase activity (By similarity).
   
 
 0.761
gpr139
G_PROTEIN_RECEP_F1_2 domain-containing protein.
      
 0.664
golph3l
Golgi phosphoprotein 3-like.
    
   0.661
knop1
Lysine-rich nucleolar protein 1.
      
 0.623
pik3c3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
   
 
 0.605
golph3
Golgi phosphoprotein 3.
    
   0.545
si:dkey-27b3.2
Si:dkey-27b3.2.
    
   0.545
hadhb
Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family.
    
   0.539
hltf
Helicase-like transcription factor.
    
 
 0.520
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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