Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
snx15Sorting nexin 15. (398 aa)    
Predicted Functional Partners:
zgc:101744
Receptor expression-enhancing protein.
    
 
 0.880
reep6
Receptor expression-enhancing protein 6; Required correct function and survival of retinal photoreceptors. Required for retinal development (By similarity). In rod photoreceptors, facilitates stability and/or trafficking of guanylate cyclases and is required to maintain endoplasmic reticulum and mitochondrial homeostasis (By similarity). May play a role in clathrin-coated intracellular vesicle trafficking of proteins from the endoplasmic reticulum to the retinal rod plasma membrane (By similarity).
    
 
 0.880
reep5
Receptor expression-enhancing protein.
    
   0.879
snx12
Sorting nexin 12.
     
 0.778
snx11
Sorting nexin 11.
     
 0.746
snx3
Sorting nexin 3.
   
 
 0.742
snx29
Sorting nexin 29.
   
 
 0.726
snx4
Sorting nexin 4.
   
  
 0.723
kif16ba
Kinesin family member 16Ba; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
    
 
 0.721
pxmp2
Peroxisomal membrane protein 2; Belongs to the peroxisomal membrane protein PXMP2/4 family.
      
 0.711
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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