Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pibf1Progesterone immunomodulatory-binding factor 1. (752 aa)    
Predicted Functional Partners:
ccdc14
Coiled-coil domain-containing 14.
    
 
 0.950
cep63
Centrosomal protein of 63 kDa; Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication. Plays a role in DNA damage response. Following DNA damage, such as double-strand breaks (DSBs), is removed from centrosomes; this leads to the inactivation of spindle assembly and delay in mitotic progression (By similarity).
   
 
 0.872
pcnt
Pericentrin.
   
 0.790
fopnl
Fgfr1op N-terminal-like.
   
 
 0.747
pcm1
Pericentriolar material 1.
   
 
 0.747
txndc12
Thioredoxin domain-containing 12 (endoplasmic reticulum).
    
 0.723
tbc1d31
TBC1 domain family, member 31.
    
 
 0.719
rhbdd3
Rhomboid domain-containing 3.
      
 0.712
ice2
Interactor of little elongator complex ELL subunit 2.
   
  
 0.707
ttll10
Tubulin tyrosine ligase-like family, member 10.
    
 
 0.694
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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