Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
mtdhbMetadherin b. (525 aa)    
Predicted Functional Partners:
snd1
Staphylococcal nuclease domain-containing protein 1.
    
 
 0.836
zcrb1
Zinc finger CCHC-type and RNA-binding motif-containing protein 1.
    
 
 0.620
ndufa12
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
      
 0.611
abcf1
ATP-binding cassette, sub-family F (GCN20), member 1.
      
 0.607
rpl4
Ribosomal protein L4.
   
   0.576
cx43
Gap junction alpha-1 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Plays an essential role in gap junction communication in the ventricles (By similarity); Belongs to the connexin family. Alpha-type (group II) subfamily.
      
 0.538
crebbpa
CREB-binding protein a.
    
 
 0.511
crebbpb
CREB-binding protein b.
    
 
 0.511
tyms
Thymidylate synthetase.
     
 0.468
lrrc59
Leucine-rich repeat-containing protein 59; Required for nuclear import of FGF1.
   
  0.466
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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