Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
vimVimentin; Belongs to the intermediate filament family. (455 aa)    
Predicted Functional Partners:
viml
Vimentin-like; Belongs to the intermediate filament family.
     
  0.935
LOC572200
Vimentin-related 1; Belongs to the intermediate filament family.
     
  0.877
vimr2
Vimentin-related 2.
    
  0.834
cdh2
Cadherin-2; Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion (By similarity). Cadherins contribute to the sorting of heterogeneous cell types, and thereby play an important role during embryonic development. Required for normal neural tube morphogenesis. Required to allow mid- and hindbrain neurons to reach and maintain their appropriate positions within the neural tube by restricting neuronal motility within the embryonic mid- and hindbrain.
    
 0.787
snai2
Snail homolog 2 (Drosophila).
   
  
 0.778
cdh1
Cadherin 1, type 1, E-cadherin (epithelial); Cadherins are calcium-dependent cell adhesion proteins.
    
 0.747
zeb1b
Zinc finger E-box-binding homeobox 1b.
      
 0.734
nes
Nestin; Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells (By similarity). Required for brain and eye development.
    
 
 0.719
twist1a
Twist family bHLH transcription factor 1a.
   
 
 0.690
zeb2a
Zinc finger E-box-binding homeobox 2a.
   
  
 0.683
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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