Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cadps2Ca++-dependent secretion activator 2. (396 aa)    
Predicted Functional Partners:
kctd12.1
Potassium channel tetramerisation domain-containing 12.1.
      
 0.782
kctd12.2
Potassium channel tetramerisation domain-containing 12.2.
      
 0.699
fam184a
Family with sequence similarity 184 member A.
      
 0.687
auts2a
Activator of transcription and developmental regulator AUTS2 a.
      
 0.633
stard5
StAR-related lipid transfer (START) domain-containing 5.
      
 0.594
GPR45
Si:dkeyp-118h3.5.
   
  
 0.573
nwd2
NACHT and WD repeat domain-containing 2.
      
 0.554
coq6
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
      
 0.533
kctd8
Potassium channel tetramerization domain-containing 8.
      
 0.521
mtnr1bb
Melatonin receptor type 1B-B; High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity (By similarity).
   
  
 0.506
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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