STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mapkapk2bMAPK-activated protein kinase 2b; Belongs to the protein kinase superfamily. (397 aa)    
Predicted Functional Partners:
hspb1
Heat shock protein, alpha-crystallin-related, 1; Belongs to the small heat shock protein (HSP20) family.
   
 0.971
mapkapk3
MAPK-activated protein kinase 3; Belongs to the protein kinase superfamily.
  
 
 
0.941
zfp36l2
Zinc finger protein 36, C3H type-like 2.
    
 0.923
zfp36l1b
Zinc finger protein 36, C3H type-like 1 like.
    
 0.919
zfp36l1a
Zinc finger protein 36, C3H type-like 1a.
    
 0.919
LOC100334443
Sb:cb81.
    
 0.919
zgc:114130
Zgc:114130.
    
 0.917
mapkapk2a
Mitogen-activated protein kinase-activated protein kinase 2a; Belongs to the protein kinase superfamily.
  
  
 
0.901
atf4a
Cyclic AMP-dependent transcription factor ATF-4; Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. May play a role in the regulation of the circadian clock (By similarity).
     
 0.901
atf4b
Activating transcription factor 4b.
     
  0.900
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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