STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hrasb-Ha-ras Harvey rat sarcoma viral oncogene homolog, like. (189 aa)    
Predicted Functional Partners:
rasa1a
RAS p21 protein activator (GTPase-activating protein) 1a.
   
 0.991
braf
B-Raf proto-oncogene, serine/threonine kinase.
    
  0.984
araf
A-Raf proto-oncogene, serine/threonine kinase.
    
  0.984
sos2
Son of sevenless homolog 2 (Drosophila).
   
 0.981
pik3cb
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
   
  0.980
pik3ca
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
  0.980
pik3r1
Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).
    
 0.979
raf1b
Raf-1 proto-oncogene, serine/threonine kinase b.
    
 0.976
raf1a
Raf-1 proto-oncogene, serine/threonine kinase a.
    
 0.975
kita
Mast/stem cell growth factor receptor kita; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine kitlg/scf and plays a role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, and in mast cell development, migration and function. Required for the migration of cells in the melanocyte lineage and the survival of embryonic melanocytes. Required for the differentiation of some, but not all, melanocytes. Not essential for hematopoiesis or primordial germ cell development.
    
  0.973
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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