Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
unm_sa808Un-named sa808. (281 aa)    
Predicted Functional Partners:
tnfrsf1a
Tumor necrosis factor receptor superfamily, member 1a.
    
 0.970
map3k1
Mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase.
   
 0.967
tnfrsf1b
Tumor necrosis factor receptor superfamily, member 1B.
   
 0.963
map3k7
Mitogen-activated protein kinase kinase kinase 7.
   
  0.959
tradd
Tumor necrosis factor receptor type 1-associated DEATH domain protein; Adapter molecule for tnfrsf1a that specifically associates with the cytoplasmic domain of activated tnfrsf1a mediating its interaction with fadd.
    
 0.957
traf6
TNF receptor-associated factor 6; E3 ubiquitin-protein ligase that mediates ubiquitination of proteins. Adapter protein that seems to play a role in signal transduction.
    
 0.949
traf3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.943
tab3
Mitogen-activated protein kinase kinase kinase 7 interacting protein 3 like.
    
 0.941
map3k5
Mitogen-activated protein kinase kinase kinase 5.
    
 0.940
ENSDARP00000146561
Si:ch211-1i11.3.
    
 0.940
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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