Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
irx2aIroquois homeobox 2a. (432 aa)    
Predicted Functional Partners:
ighd
Immunoglobulin heavy constant delta.
      
 0.780
gmnc
Geminin coiled-coil domain-containing.
      
 0.690
odf3b
Outer dense fiber protein 3-B.
      
 0.680
irx3a
Iroquois 3 homeobox protein.
   
  
0.637
irx4a
Iroquois homeobox protein 4a.
   
  
0.616
ppargc1a
Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.
   
  
 0.602
sez6a
Seizure-related 6 homolog a.
    
 
 0.596
pcp4a
Purkinje cell protein 4a.
      
 0.594
irx1a
Iroquois homeobox protein 1, a.
   
  
0.591
ptgs1
Prostaglandin-endoperoxide synthase 1.
    
 
 0.585
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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