Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
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[Homology]
Score
prkag1Protein kinase, AMP-activated, gamma 1 non-catalytic subunit. (330 aa)    
Predicted Functional Partners:
prkab1b
Protein kinase, AMP-activated, beta 1 non-catalytic subunit, b.
   
 0.999
prkab1a
Protein kinase, AMP-activated, beta 1 non-catalytic subunit, a.
   
 0.999
prkaa1
Non-specific serine/threonine protein kinase.
   
 0.999
prkaa2
Non-specific serine/threonine protein kinase.
   
 0.999
E7F9H4_DANRE
AMPKBI domain-containing protein.
   
 0.997
prkag2b
Protein kinase, AMP-activated, gamma 2 non-catalytic subunit b.
  
  
0.994
prkag3b
Protein kinase, AMP-activated, gamma 3b non-catalytic subunit.
  
  
0.993
E7FEF7_DANRE
Si:ch73-62l21.1.
   
 0.973
stk11
Serine/threonine kinase 11; Belongs to the protein kinase superfamily.
   
 0.967
acacb
Acetyl-CoA carboxylase beta.
   
 0.955
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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