Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rpp14Ribonuclease P/MRP 14 subunit. (125 aa)    
Predicted Functional Partners:
scp2a
Sterol carrier protein 2a; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.990
scp2b
Sterol carrier protein 2b.
   
 0.990
acaa1
Acetyl-Coenzyme A acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.989
acox1
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
  
 0.961
cat
Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide; Belongs to the catalase family.
   
 
 0.897
hibch
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA (By similarity); Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.869
mlsl
Malate synthase-like.
   
 
 0.868
eci2
Enoyl-CoA delta isomerase 2.
  
 0.866
acox3
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
  
 0.848
acoxl
Acyl-CoA oxidase-like.
  
 0.848
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (18%) [HD]