STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mmp23bbMatrix metallopeptidase 23bb. (377 aa)    
Predicted Functional Partners:
LOC100001991
ADAM metallopeptidase with thrombospondin type 1 motif, 15b.
   
 
 0.743
LOC100002059
ADAM metallopeptidase with thrombospondin type 1 motif, 15b.
   
 
 0.739
noc2l
NOC2-like nucleolar-associated transcriptional repressor.
      
 0.736
luzp1
Leucine zipper protein 1.
      
 0.661
LOC568792
ADAM metallopeptidase with thrombospondin type 1 motif, 16.
   
 
 0.599
supv3l1
ATP-dependent RNA helicase SUPV3L1, mitochondrial; Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation o [...]
      
 0.581
spint1b
Serine peptidase inhibitor, Kunitz type 1 b.
      
 0.559
zfyve9a
Zinc finger, FYVE domain-containing 9a.
      
 0.543
timp2b
TIMP metallopeptidase inhibitor 2b.
   
 
 0.502
X1WBT0_DANRE
Si:dkey-105h12.2.
    
 
 0.491
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.