STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
neflbNeurofilament, light polypeptide b; Belongs to the intermediate filament family. (579 aa)    
Predicted Functional Partners:
dusp12
Dual-specificity phosphatase 12.
    
 
 0.748
sh3tc2
SH3 domain and tetratricopeptide repeats 2.
      
 0.582
iffo1a
Intermediate filament family orphan 1a; Belongs to the intermediate filament family.
      
 0.570
bard1
BRCA1-associated RING domain 1.
   
 
 0.562
gdap1
Ganglioside-induced differentiation-associated protein 1.
   
  
 0.551
iffo2b
Intermediate filament family orphan 2b; Belongs to the intermediate filament family.
      
 0.544
dlg4
Disks large homolog 4; Plays a role in synapse assembly and function. Plays a role in synaptic plasticity.
    
 0.541
camk2b1
Calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1.
   
 0.539
camk2a
Calcium/calmodulin-dependent protein kinase II alpha; Belongs to the protein kinase superfamily.
   
 0.536
mpz
Myelin protein zero.
      
 0.536
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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