Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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nudt21Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (228 aa)    
Predicted Functional Partners:
cpsf6
Cleavage and polyadenylation specificity factor subunit 6; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]
   
 0.999
pcf11
PCF11 cleavage and polyadenylation factor subunit.
    
 0.998
fip1l1b
Pre-mRNA 3'-end-processing factor FIP1; Involved in mRNA processing; Belongs to the FIP1 family.
   
 0.961
cstf2
Cleavage stimulation factor, 3' pre-RNA, subunit 2.
   
 0.954
cpsf4
Cleavage and polyadenylation-specific factor 4.
    
 0.945
cstf1
Cleavage stimulation factor, 3' pre-RNA, subunit 1.
   
 
 0.939
sympk
Symplekin.
     
 0.932
cpsf2
Cleavage and polyadenylation specificity factor subunit 2.
   
 0.918
cpsf1
Cleavage and polyadenylation-specific factor 1.
   
 
 0.911
cpsf3
Cleavage and polyadenylation-specific factor 3.
   
 0.906
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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