STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dpy30Dpy-30 histone methyltransferase complex regulatory subunit. (106 aa)    
Predicted Functional Partners:
wdr5
WD repeat domain 5.
   
 0.999
rbbp5
Retinoblastoma-binding protein 5.
   
 0.999
ash2l
Ash2-like, histone lysine methyltransferase complex subunit.
    
 0.999
wdr82
WD repeat-containing protein 82; Component of a chromatin regulatory complex involved in regulating chromatin structure in the nucleus; Belongs to the WD repeat SWD2 family.
   
 0.982
setd1ba
Histone-lysine N-methyltransferase SETD1B-A; Histone methyltransferase that specifically methylates 'Lys- 4' of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring 'Lys-9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.
    
 0.958
cxxc1b
CXXC finger protein 1b.
    
 0.950
setd1bb
SET domain-containing 1B, histone lysine methyltransferase b.
    
 0.942
setd1a
SET domain-containing 1A, histone lysine methyltransferase.
    
 0.942
cxxc1a
CXXC finger protein 1a.
    
 0.925
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
   
   0.906
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.