Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rcan1aRegulator of calcineurin 1a. (210 aa)    
Predicted Functional Partners:
lmod2a
Leiomodin 2 (cardiac) a.
      
 0.838
srrm1
Serine/arginine repetitive matrix 1.
      
 0.711
txndc17
Thioredoxin domain-containing protein 17; Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide (By similarity); Belongs to the thioredoxin family.
      
 0.686
apcdd1l
Adenomatosis polyposis coli down-regulated 1-like.
      
 0.683
rtn4rl2a
Reticulon 4 receptor-like 2 a.
      
 0.661
hpcal1
Hippocalcin-like 1.
    
 
 0.652
ppp3r1b
Protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b.
    
 
 0.612
ppp3r1a
Protein phosphatase 3, regulatory subunit B, alpha a.
    
 
 0.612
ppp3ca
Serine/threonine-protein phosphatase.
    
 
 0.603
ppp3cb
Serine/threonine-protein phosphatase.
    
 
 0.603
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.