STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rcan1aRegulator of calcineurin 1a. (210 aa)    
Predicted Functional Partners:
lmod2a
Leiomodin 2 (cardiac) a.
      
 0.862
srrm1
Serine/arginine repetitive matrix 1.
      
 0.804
txndc17
Thioredoxin domain-containing protein 17; Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide (By similarity); Belongs to the thioredoxin family.
      
 0.743
apcdd1l
Adenomatosis polyposis coli down-regulated 1-like.
      
 0.741
myo1ca
Unconventional myosin-Ic; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity).
   
  
 0.669
myo1cb
Myosin Ic, paralog b; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
      
 0.661
hspb11
Heat shock protein beta-11; Belongs to the small heat shock protein (HSP20) family.
      
 0.645
ppp3cb
Serine/threonine-protein phosphatase.
   
 
 0.596
ppp3ca
Serine/threonine-protein phosphatase.
   
 
 0.593
ppp3ccb
Serine/threonine-protein phosphatase.
    
 
 0.591
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.