Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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[Homology]
Score
pfasPhosphoribosylformylglycinamidine synthase. (1314 aa)    
Predicted Functional Partners:
gart
Phosphoribosylglycinamide formyltransferase.
   
 0.996
atic
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.
   
  
 0.801
ppat
Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
   
 
 0.792
paics
Phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase.
   
 
 0.772
adsl
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
 
 0.726
nsrp1
Nuclear speckle splicing regulatory protein 1; Belongs to the NSRP1 family.
      
 0.723
ipo9
Importin 9.
   
 
 0.705
tnpo3
Transportin 3.
     
 0.698
ipo11
Importin 11.
   
 
 0.698
kpnb1
Karyopherin (importin) beta 1.
     
 0.692
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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