| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| clns1a | ddx20 | ENSDARP00000133397 | ENSDARP00000143528 | Chloride channel, nucleotide-sensitive, 1A. | Probable ATP-dependent RNA helicase DDX20; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins are trapped in an inactive complex. The SMN complex triggers the assembly of core snRNPs and their transport to the nucleus. May also pla [...] | 0.474 |
| clns1a | gemin2 | ENSDARP00000133397 | ENSDARP00000149265 | Chloride channel, nucleotide-sensitive, 1A. | Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. | 0.594 |
| clns1a | gemin5 | ENSDARP00000133397 | ENSDARP00000113067 | Chloride channel, nucleotide-sensitive, 1A. | Gem (nuclear organelle)-associated protein 5. | 0.659 |
| clns1a | gemin7 | ENSDARP00000133397 | ENSDARP00000060097 | Chloride channel, nucleotide-sensitive, 1A. | Gem (nuclear organelle)-associated protein 7. | 0.600 |
| clns1a | gemin8 | ENSDARP00000133397 | ENSDARP00000053932 | Chloride channel, nucleotide-sensitive, 1A. | Gem (nuclear organelle)-associated protein 8. | 0.616 |
| clns1a | smn1 | ENSDARP00000133397 | ENSDARP00000017636 | Chloride channel, nucleotide-sensitive, 1A. | Survival motor neuron protein 1; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs. Required in motor neurons and proprioceptive neurons to ensure correct U12 intron splicing and proper levels of tmem41b mRNA. Required for the maturation of motor neuron axonal branches and dendrites. | 0.957 |
| clns1a | snrpd1 | ENSDARP00000133397 | ENSDARP00000027770 | Chloride channel, nucleotide-sensitive, 1A. | Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. | 0.997 |
| clns1a | snrpd2 | ENSDARP00000133397 | ENSDARP00000059193 | Chloride channel, nucleotide-sensitive, 1A. | Small nuclear ribonucleoprotein Sm D2. | 0.935 |
| clns1a | snrpe | ENSDARP00000133397 | ENSDARP00000050295 | Chloride channel, nucleotide-sensitive, 1A. | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. | 0.947 |
| clns1a | snrpg | ENSDARP00000133397 | ENSDARP00000133036 | Chloride channel, nucleotide-sensitive, 1A. | Small nuclear ribonucleoprotein G. | 0.883 |
| ddx20 | clns1a | ENSDARP00000143528 | ENSDARP00000133397 | Probable ATP-dependent RNA helicase DDX20; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins are trapped in an inactive complex. The SMN complex triggers the assembly of core snRNPs and their transport to the nucleus. May also pla [...] | Chloride channel, nucleotide-sensitive, 1A. | 0.474 |
| ddx20 | gemin2 | ENSDARP00000143528 | ENSDARP00000149265 | Probable ATP-dependent RNA helicase DDX20; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins are trapped in an inactive complex. The SMN complex triggers the assembly of core snRNPs and their transport to the nucleus. May also pla [...] | Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. | 0.992 |
| ddx20 | gemin5 | ENSDARP00000143528 | ENSDARP00000113067 | Probable ATP-dependent RNA helicase DDX20; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins are trapped in an inactive complex. The SMN complex triggers the assembly of core snRNPs and their transport to the nucleus. May also pla [...] | Gem (nuclear organelle)-associated protein 5. | 0.992 |
| ddx20 | gemin7 | ENSDARP00000143528 | ENSDARP00000060097 | Probable ATP-dependent RNA helicase DDX20; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins are trapped in an inactive complex. The SMN complex triggers the assembly of core snRNPs and their transport to the nucleus. May also pla [...] | Gem (nuclear organelle)-associated protein 7. | 0.987 |
| ddx20 | gemin8 | ENSDARP00000143528 | ENSDARP00000053932 | Probable ATP-dependent RNA helicase DDX20; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins are trapped in an inactive complex. The SMN complex triggers the assembly of core snRNPs and their transport to the nucleus. May also pla [...] | Gem (nuclear organelle)-associated protein 8. | 0.982 |
| ddx20 | smn1 | ENSDARP00000143528 | ENSDARP00000017636 | Probable ATP-dependent RNA helicase DDX20; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins are trapped in an inactive complex. The SMN complex triggers the assembly of core snRNPs and their transport to the nucleus. May also pla [...] | Survival motor neuron protein 1; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs. Required in motor neurons and proprioceptive neurons to ensure correct U12 intron splicing and proper levels of tmem41b mRNA. Required for the maturation of motor neuron axonal branches and dendrites. | 0.993 |
| ddx20 | snrpd1 | ENSDARP00000143528 | ENSDARP00000027770 | Probable ATP-dependent RNA helicase DDX20; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins are trapped in an inactive complex. The SMN complex triggers the assembly of core snRNPs and their transport to the nucleus. May also pla [...] | Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. | 0.757 |
| ddx20 | snrpd2 | ENSDARP00000143528 | ENSDARP00000059193 | Probable ATP-dependent RNA helicase DDX20; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins are trapped in an inactive complex. The SMN complex triggers the assembly of core snRNPs and their transport to the nucleus. May also pla [...] | Small nuclear ribonucleoprotein Sm D2. | 0.450 |
| ddx20 | snrpe | ENSDARP00000143528 | ENSDARP00000050295 | Probable ATP-dependent RNA helicase DDX20; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins are trapped in an inactive complex. The SMN complex triggers the assembly of core snRNPs and their transport to the nucleus. May also pla [...] | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. | 0.856 |
| ddx20 | snrpg | ENSDARP00000143528 | ENSDARP00000133036 | Probable ATP-dependent RNA helicase DDX20; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins are trapped in an inactive complex. The SMN complex triggers the assembly of core snRNPs and their transport to the nucleus. May also pla [...] | Small nuclear ribonucleoprotein G. | 0.700 |