Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lhx6LIM homeobox 6. (375 aa)    
Predicted Functional Partners:
dlx1a
Homeobox protein Dlx1a.
   
  
 0.846
dlx2a
Homeobox protein Dlx2a; Involved in the development of the inner ear; Belongs to the distal-less homeobox family.
   
  
 0.829
nkx2.1
NK2 homeobox 1b.
   
 
 0.827
nkx2.4b
NK2 homeobox 1a.
   
 
 0.822
edaradd
EDAR-associated death domain.
      
 0.786
barx1
Homeobox protein BarH-like 1; Transcription factor, is involved in craniofacial development, and in stomach organogenesis; Belongs to the BAR homeobox family.
   
 
 0.768
dlx2b
Homeobox protein Dlx2b.
   
  
 0.746
entpd5a
Ectonucleoside triphosphate diphosphohydrolase 5a; Belongs to the GDA1/CD39 NTPase family.
   
  
 0.740
sst2
Somatostatin 2.
   
  
 0.716
pold1
DNA polymerase.
    
 
 0.702
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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