Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1039 aa)    
Predicted Functional Partners:
pik3r1
Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).
   
 0.997
pik3cb
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
  
  
0.994
pik3r2
Phosphoinositide-3-kinase, regulatory subunit 2 (beta).
   
 0.988
pik3r3a
Phosphoinositide-3-kinase, regulatory subunit 3a (gamma).
   
 0.988
mtor
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
    
 0.980
rras
Related RAS viral (R-ras) oncogene homolog.
    
 0.972
rras2
Related RAS viral (R-ras) oncogene homolog 2.
    
 0.972
cdc42l
Cell division cycle 42,-like.
    
 0.971
pik3ca
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
     
 
0.968
pik3r6b
Phosphoinositide-3-kinase, regulatory subunit 6b.
    
  0.967
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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