Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
cishbCytokine-inducible SH2-containing protein b. (213 aa)    
Predicted Functional Partners:
cul5a
Cullin 5a; Belongs to the cullin family.
   
 0.900
epor
Erythropoietin receptor.
    
 
 0.819
cul5b
Cullin 5b; Belongs to the cullin family.
   
 
 0.809
prlra
Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin; Belongs to the type I cytokine receptor family. Type 1 subfamily.
    
 0.750
socs5a
Suppressor of cytokine-signaling 5a.
     
0.749
eloca
Elongin C paralog a; Belongs to the SKP1 family.
    
 0.735
rnf7
Ring finger protein 7.
   
 0.705
elob
Elongin B.
    
 
 0.705
X1WBN9_DANRE
Uncharacterized protein.
    
 
 0.705
socs3b
Suppressor of cytokine-signaling 3b.
   
 
0.636
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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