Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
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[Homology]
Score
rom1aRetinal outer segment membrane protein 1a. (346 aa)    
Predicted Functional Partners:
pnpla8
Patatin-like phospholipase domain-containing 8.
      
 0.730
rnf128a
Ring finger protein 128a.
    
 
 0.704
LOC100536511
Si:dkeyp-86f7.4.
    
 
 0.704
dusp6
Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
      
 0.699
glyr1
Putative oxidoreductase GLYR1; May have oxidoreductase activity. Regulates p38 MAP kinase activity by mediating stress activation of mapk14 and specifically regulating mapk14 signaling; Belongs to the HIBADH-related family. NP60 subfamily.
      
 0.670
LOC101882550
Si:dkeyp-70f9.7.
      
 0.660
pde6gb
Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b.
   
  
 0.627
ppp1cb
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
      
 0.622
ppp1cbl
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
      
 0.622
cplx4c
Complexin 4c.
      
 0.600
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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