Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
eif4g2aEukaryotic translation initiation factor 4, gamma 2a. (891 aa)    
Predicted Functional Partners:
eif4e1b
Eukaryotic translation initiation factor 4E-1B; Does not appear to be a mRNA-cap-binding protein.
   
 0.954
eif4ea
Eukaryotic translation initiation factor 4E-1A; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
   
 0.954
eif4eb
Eukaryotic translation initiation factor 4eb; Belongs to the eukaryotic initiation factor 4E family.
   
 0.945
eif4e3
Eukaryotic translation initiation factor 4E type 3; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis. Belongs to the eukaryotic initiation factor 4E family.
   
 0.941
eif4g2b
Eukaryotic translation initiation factor 4, gamma 2b.
  
 
 
0.927
eif4e2rs1
Eukaryotic translation initiation factor 4E family member 2-related sequence 1; Belongs to the eukaryotic initiation factor 4E family.
   
  0.904
eif4e2
Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family.
    
  0.903
inka1a
PAK4-inhibitor inka1; Inhibitor of the serine/threonine-protein kinase pak4/pak5 (By similarity). Acts by binding pak4/pak5 in a substrate-like manner, inhibiting the protein kinase activity (By similarity). Required for the proper migration of neural crest cells during embryonic development, probably by inhibiting pak4/pak5. Belongs to the INKA family.
      
 0.891
eif4a1b
Eukaryotic translation initiation factor 4A, isoform 1B; Belongs to the DEAD box helicase family.
   
 
 0.889
eif4a1a
Eukaryotic translation initiation factor 4A, isoform 1A.
   
 
 0.860
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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