Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
Experiments
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[Homology]
Score
fbxl2F-box and leucine-rich repeat protein 2. (432 aa)    
Predicted Functional Partners:
ptar1
Protein prenyltransferase alpha subunit repeat-containing protein 1; Belongs to the protein prenyltransferase subunit alpha family.
    
 
 0.861
cul1b
Cullin 1b; Belongs to the cullin family.
   
 
 0.843
skp1
S-phase kinase-associated protein 1A; Belongs to the SKP1 family.
    
 
 0.841
fbxo3
F-box protein 3.
    
 
 0.810
fbxo11a
F-box protein 11a.
   
  
 0.808
cul1a
Cullin 1a; Belongs to the cullin family.
    
 
 0.801
fbxl8
F-box and leucine-rich repeat protein 8.
      
 0.719
fbxo25
F-box only protein 25.
   
  
 0.715
rabggtb
Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX.
    
 
 0.697
fbxl18
F-box and leucine-rich repeat protein 18.
      
 0.686
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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