Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ttc14Tetratricopeptide repeat domain 14. (665 aa)    
Predicted Functional Partners:
pnisr
PNN-interacting serine/arginine-rich protein.
   
   0.862
mbtps2
Membrane-bound transcription factor peptidase, site 2.
   
  
 0.845
ess2
Ess-2-splicing factor homolog.
   
 
 0.816
mccc1
Methylcrotonoyl-CoA carboxylase 1 (alpha).
      
 0.805
dnajc19
Mitochondrial import inner membrane translocase subunit TIM14; Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity).
      
 0.802
ttc39c
Tetratricopeptide repeat protein 39C.
      
 0.754
rnpc3
RNA-binding region-containing protein 3; Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns. U12-type introns comprise less than 1% of all non-coding sequences.
   
   0.719
cldn18
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
      
 0.695
snip1
Smad nuclear-interacting protein.
   
   0.690
fra10ac1
FRA10A-associated CGG repeat 1.
    
 
 0.668
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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