Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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[Homology]
Score
galcbGalactosylceramidase b. (664 aa)    
Predicted Functional Partners:
asah1b
N-acylsphingosine amidohydrolase (acid ceramidase) 1b; Belongs to the acid ceramidase family.
   
 
 0.982
cerk
Ceramide kinase.
     
 0.979
asah1a
N-acylsphingosine amidohydrolase (acid ceramidase) 1a; Belongs to the acid ceramidase family.
   
 
 0.978
ugt8
UDP glycosyltransferase 8; Belongs to the UDP-glycosyltransferase family.
     
 0.977
gba2
Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.
     
 0.976
gba
Glucosylceramidase.
     
 0.974
sgms1
Sphingomyelin synthase 1.
   
 
 0.973
arsa
Arylsulfatase A.
     
 0.969
asah2
Neutral ceramidase; Plasma membrane ceramidase that hydrolyzes sphingolipid ceramides into sphingosine and free fatty acids at neutral pH. Ceramides, sphingosine, and its phosphorylated form sphingosine-1-phosphate are bioactive lipids that mediate cellular signaling pathways regulating several biological processes including cell proliferation, apoptosis and differentiation. Also catalyzes the reverse reaction allowing the synthesis of ceramides from fatty acids and sphingosine. Together with sphingomyelinase, participates in the production of sphingosine and sphingosine-1-phosphate fr [...]
     
 0.966
cers6
Ceramide synthase 6.
     
 0.963
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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