Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
xiapX-linked inhibitor of apoptosis. (405 aa)    
Predicted Functional Partners:
casp9
Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
   
 0.999
birc5a
Baculoviral IAP repeat-containing 5a.
    
0.998
diabloa
Diablo, IAP-binding mitochondrial protein a.
   
 0.998
casp3a
Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.
   
 0.997
tab1
TGF-beta-activated kinase 1/MAP3K7-binding protein 1.
   
 0.995
birc2
Baculoviral IAP repeat-containing 2.
   
0.995
ripk1l
Receptor (TNFRSF)-interacting serine-threonine kinase 1,-like.
   
 0.991
traf2b
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.984
birc7
Baculoviral IAP repeat-containing 7.
   
  0.981
ripk2
Receptor-interacting serine-threonine kinase 2.
   
 0.981
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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