STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mcambMelanoma cell adhesion molecule b. (617 aa)    
Predicted Functional Partners:
esyt3
Extended synaptotagmin-like protein 3.
      
 0.566
arhgef7a
Rho guanine nucleotide exchange factor (GEF) 7a.
      
 0.565
mark2a
Non-specific serine/threonine protein kinase.
      
 0.543
edil3a
EGF-like repeats and discoidin I-like domains 3a.
      
 0.543
arl4d
ADP-ribosylation factor-like 4D.
    
 
 0.493
myo9aa
Unconventional myosin-IXAa; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Regulates Rho by stimulating it's GTPase activity in neurons (By similarity). Required for the regulation of neurite branching and motor neuron axon guidance.
      
 0.480
mmp17a
Matrix metallopeptidase 17a.
    
 
 0.478
tmem255a
Transmembrane protein 255A.
      
 0.453
slc12a8
Solute carrier family 12 member 8.
      
 0.453
lrp10
Low density lipoprotein receptor-related protein 10.
      
 0.452
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.