Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
cmss1Protein CMSS1; Belongs to the CMS1 family. (292 aa)    
Predicted Functional Partners:
utp23
UTP23 small subunit processome component.
   
  
 0.925
wdr36
WD repeat domain 36.
   
   0.879
nol6
Nucleolar protein 6.
   
 
 0.877
heatr1
HEAT repeat-containing protein 1; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. Required for cell survival in the CNS through its role in rRNA synthesis and processing.
   
   0.872
utp4
Cirrhosis, autosomal recessive 1A (Cirhin).
   
   0.860
ltv1
Protein LTV1 homolog; Belongs to the LTV1 family.
   
  
 0.846
nop53
Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family.
   
    0.846
rrp1
Ribosomal RNA-processing 1.
   
    0.804
rbm28
RNA-binding motif protein 28.
   
  
 0.803
esf1
ESF1, nucleolar pre-rRNA-processing protein, homolog (S. cerevisiae).
   
    0.787
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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