Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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mul1aMitochondrial ubiquitin ligase activator of nfkb 1-A; E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. (341 aa)    
Predicted Functional Partners:
mfn2
Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
    
 0.972
tomm70a
Translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae).
     
 0.960
rhot2
Mitochondrial Rho GTPase 2; Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (By similarity).
     
 0.949
rps27a
Ribosomal protein S27a.
    
  0.948
gabarapl2
GABA(A) receptor-associated protein-like 2.
    
 0.947
zgc:92606
Zgc:92606.
    
  0.944
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
     
  0.944
mul1b
Mitochondrial E3 ubiquitin protein ligase 1b.
     
  0.944
map1lc3cl
Microtubule-associated protein 1 light chain 3 gamma,-like.
    
  0.944
map1lc3c
Microtubule-associated protein 1 light chain 3 gamma.
    
  0.944
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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