STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
wdr55WD repeat-containing protein 55; Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis (By similarity). (386 aa)    
Predicted Functional Partners:
lcp2a
Lymphocyte cytosolic protein 2a.
      
 0.995
ik
IK cytokine.
 
      0.897
zmat2
Zinc finger, matrin-type 2.
   
  
 0.866
wdr12
Ribosome biogenesis protein wdr12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
   
 
 0.855
slbp2
Stem-loop-binding protein 2.
      
 0.810
pcdh2aa1
Protocadherin 2 alpha a 1.
      
 0.744
ccl25a
Chemokine (C-C motif) ligand 25a.
      
 0.735
ttc27
Tetratricopeptide repeat domain 27.
   
    0.697
taf7
TAF7 RNA polymerase II, TATA box-binding protein (TBP)-associated factor.
      
 0.697
nifk
MKI67 FHA domain-interacting nucleolar phosphoprotein; Plays an essential role in early embryonic development.
   
   0.689
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.