STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cyp2ad2Cytochrome P450, family 2, subfamily AD, polypeptide 2; Belongs to the cytochrome P450 family. (492 aa)    
Predicted Functional Partners:
mtfr1
Mitochondrial fission regulator 1; May play a role in mitochondrial aerobic respiration. May also regulate mitochondrial organization and fission (By similarity).
      
 0.807
nrxn1b
Neurexin-1b; Neuronal cell surface protein that may be involved in cell recognition and cell adhesion; Belongs to the neurexin family.
   
  
 0.747
cyp3a65
Cytochrome P450, family 3, subfamily A, polypeptide 65; Belongs to the cytochrome P450 family.
  
0.714
cyp3c3
Cytochrome P450, family 3, subfamily c, polypeptide 3; Belongs to the cytochrome P450 family.
  
0.712
cyp3c1
Cytochrome P450, family 3, subfamily c, polypeptide 1; Belongs to the cytochrome P450 family.
  
0.681
cyp3c4
Cytochrome P450, family 3, subfamily C, polypeptide 4; Belongs to the cytochrome P450 family.
  
0.681
tpmt.1
Probable thiopurine S-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
   
 
 0.678
miox
Inositol oxygenase; Belongs to the myo-inositol oxygenase family.
   
  
 0.620
hsdl2
Hydroxysteroid dehydrogenase-like protein 2; Has apparently no steroid dehydrogenase activity. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.607
slco1d1
Solute carrier organic anion transporter family member.
   
  
 0.602
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.