Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tspan7Tetraspanin. (251 aa)    
Predicted Functional Partners:
E7FFT4_DANRE
Si:ch73-109i22.2.
      
 0.513
E7FDH2_DANRE
Si:ch211-112g6.4.
      
 0.513
pigk
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
      
 0.503
ypel1
Protein yippee-like; Belongs to the yippee family.
   
  
 0.501
cxcl12a
Chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1); Belongs to the intercrine alpha (chemokine CxC) family.
      
 0.468
tspan12
Tetraspanin.
   
  
0.458
dhrs7b
Dehydrogenase/reductase SDR family member 7B; Putative oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 
 0.440
flot1b
Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.
   
  
 0.438
ttc1
Tetratricopeptide repeat domain 1.
      
 0.436
atpaf1
ATP synthase mitochondrial F1 complex assembly factor 1; May play an essential role for the assembly of the mitochondrial F1-F0 complex; Belongs to the ATP11 family.
      
 0.431
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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