Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
f7Coagulation factor VII. (433 aa)    
Predicted Functional Partners:
f3b
Coagulation factor IIIb.
    
 0.970
f10
Coagulation factor X.
  
 
 
0.782
f9b
Coagulation factor IXb.
  
 
 
0.772
furina
Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family.
     
 0.759
plgrkt
Plasminogen receptor, C-terminal lysine transmembrane protein.
    
 
 0.664
serpinc1
Serine (Or cysteine) proteinase inhibitor, clade C (Antithrombin), member 1; Belongs to the serpin family.
   
 0.618
fgb
Fibrinogen, B beta polypeptide.
   
 
 0.607
f2
Coagulation factor II (thrombin); Belongs to the peptidase S1 family.
  
 
0.569
snx16
Sorting nexin 16.
    
 
 0.567
sdf2l1
Stromal cell-derived factor 2-like 1.
    
 
 0.561
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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