STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pdpk1b3-phosphoinositide-dependent protein kinase 1b. (537 aa)    
Predicted Functional Partners:
sgk1
Serine/threonine-protein kinase Sgk1; Protein kinase that may play an important role in cellular stress response. May be involved in the regulation of processes such as cell survival, neuronal excitability and renal sodium excretion (By similarity); Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
    
0.989
akt3b
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
0.983
akt2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
0.968
pik3ca
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.960
A3KQ53_DANRE
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.953
pik3r1
Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).
     
 0.953
sgk3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.946
pik3cb
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
    
 0.945
rps6kb1a
Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
    
 0.943
pik3r2
Phosphoinositide-3-kinase, regulatory subunit 2 (beta).
     
 0.941
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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