Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gpr27G protein-coupled receptor 27. (371 aa)    
Predicted Functional Partners:
cpt1cb
Carnitine palmitoyltransferase 1Cb; Belongs to the carnitine/choline acetyltransferase family.
      
 0.712
rgs17
Regulator of G protein-signaling 17.
   
  
 0.603
gpr25
G protein-coupled receptor 25; Belongs to the G-protein coupled receptor 1 family.
      
 0.600
rgs8
Regulator of G-protein signaling 8; Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptors and dopamine receptors. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Modulates the activity of potassium channels that are activated in response to G protein-coupled receptor signaling.
      
 0.579
gpr12
G protein-coupled receptor 12; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.562
crata
Carnitine O-acetyltransferase a; Belongs to the carnitine/choline acetyltransferase family.
      
 0.484
grpr
Gastrin-releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.472
gpr160
Similar to Probable G-protein coupled receptor 160.
      
 0.463
gpr22a
G-protein coupled receptor 22; Orphan G-protein coupled receptor that regulates cilia length and structure in the Kupffer's vesicle leading to the left-right asymmetry development by establishing a directional fluid flow.
   
  
 0.460
scg3
Secretogranin-3.
   
  
 0.454
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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