Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gcc1GRIP and coiled-coil domain-containing 1. (802 aa)    
Predicted Functional Partners:
bysl
Bystin-like.
   
 
 0.921
tmf1
TATA element modulatory factor 1.
   
 
 0.917
pwp2h
PWP2 small subunit processome component.
   
 
 0.904
aatf
Apoptosis-antagonizing transcription factor.
   
 
 0.900
heatr1
HEAT repeat-containing protein 1; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. Required for cell survival in the CNS through its role in rRNA synthesis and processing.
   
 
 0.900
nob1
RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family.
   
 
 0.890
dimt1l
rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
   
 
 0.888
nop14
NOP14 nucleolar protein homolog (yeast).
   
 
 0.885
imp4
IMP4, U3 small nucleolar ribonucleoprotein, homolog (Yeast).
   
 
 0.882
ltv1
Protein LTV1 homolog; Belongs to the LTV1 family.
   
 
 0.872
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (16%) [HD]