STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
igfbp2bInsulin-like growth factor-binding protein 2-B; IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. (265 aa)    
Predicted Functional Partners:
MDFIC2
Si:dkey-58f6.2.
      
 0.744
gas2l3
Growth arrest-specific 2-like 3.
   
  
 0.720
igflr1
IGF-like family receptor 1.
      
 0.669
lmf1
Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family.
      
 0.644
mlnr
Motilin receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.618
MDFIC
Si:ch211-262n1.4.
      
 0.570
fgfbp3
Fibroblast growth factor-binding protein 3.
      
 0.565
mstna
Growth differentiation factor 8, like.
   
  
 0.563
frs3
Fibroblast growth factor receptor substrate 3.
      
 0.541
frs2a
Fibroblast growth factor receptor substrate 2a.
      
 0.540
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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