tab2 protein (Danio rerio) - STRING interaction network

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tab2

TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; May play a role in signaling pathway. Involved in heart development. (711 aa)

Predicted Functional Partners:

traf6

0.998

map3k7

0.991

ripk1l

0.991

chuk

0.989

ikbkg

0.986

irak1

0.984

irak4

0.979

tab1

0.977

tradd

0.967

tab3

0.961

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
chuk	ikbkg	ENSDARP00000013115	ENSDARP00000027612	Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	0.997
chuk	irak1	ENSDARP00000013115	ENSDARP00000118154	Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.	Interleukin-1 receptor-associated kinase 1.	0.967
chuk	irak4	ENSDARP00000013115	ENSDARP00000135636	Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.	Interleukin-1 receptor-associated kinase 4.	0.969
chuk	map3k7	ENSDARP00000013115	ENSDARP00000006286	Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.	Mitogen-activated protein kinase kinase kinase 7.	0.958
chuk	ripk1l	ENSDARP00000013115	ENSDARP00000014604	Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.	Receptor (TNFRSF)-interacting serine-threonine kinase 1,-like.	0.958
chuk	tab1	ENSDARP00000013115	ENSDARP00000053182	Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.	TGF-beta-activated kinase 1/MAP3K7-binding protein 1.	0.859
chuk	tab2	ENSDARP00000013115	ENSDARP00000019647	Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; May play a role in signaling pathway. Involved in heart development.	0.989
chuk	tab3	ENSDARP00000013115	ENSDARP00000083707	Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.	Mitogen-activated protein kinase kinase kinase 7 interacting protein 3 like.	0.977
chuk	tradd	ENSDARP00000013115	ENSDARP00000052344	Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.	Tumor necrosis factor receptor type 1-associated DEATH domain protein; Adapter molecule for tnfrsf1a that specifically associates with the cytoplasmic domain of activated tnfrsf1a mediating its interaction with fadd.	0.827
chuk	traf6	ENSDARP00000013115	ENSDARP00000036715	Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.	TNF receptor-associated factor 6; E3 ubiquitin-protein ligase that mediates ubiquitination of proteins. Adapter protein that seems to play a role in signal transduction.	0.995
ikbkg	chuk	ENSDARP00000027612	ENSDARP00000013115	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.	0.997
ikbkg	irak1	ENSDARP00000027612	ENSDARP00000118154	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Interleukin-1 receptor-associated kinase 1.	0.780
ikbkg	irak4	ENSDARP00000027612	ENSDARP00000135636	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Interleukin-1 receptor-associated kinase 4.	0.940
ikbkg	map3k7	ENSDARP00000027612	ENSDARP00000006286	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Mitogen-activated protein kinase kinase kinase 7.	0.958
ikbkg	ripk1l	ENSDARP00000027612	ENSDARP00000014604	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Receptor (TNFRSF)-interacting serine-threonine kinase 1,-like.	0.952
ikbkg	tab1	ENSDARP00000027612	ENSDARP00000053182	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	TGF-beta-activated kinase 1/MAP3K7-binding protein 1.	0.455
ikbkg	tab2	ENSDARP00000027612	ENSDARP00000019647	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; May play a role in signaling pathway. Involved in heart development.	0.986
ikbkg	tab3	ENSDARP00000027612	ENSDARP00000083707	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Mitogen-activated protein kinase kinase kinase 7 interacting protein 3 like.	0.981
ikbkg	tradd	ENSDARP00000027612	ENSDARP00000052344	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Tumor necrosis factor receptor type 1-associated DEATH domain protein; Adapter molecule for tnfrsf1a that specifically associates with the cytoplasmic domain of activated tnfrsf1a mediating its interaction with fadd.	0.861
ikbkg	traf6	ENSDARP00000027612	ENSDARP00000036715	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	TNF receptor-associated factor 6; E3 ubiquitin-protein ligase that mediates ubiquitination of proteins. Adapter protein that seems to play a role in signal transduction.	0.965

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