STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fam120aFamily with sequence similarity 120A. (1044 aa)    
Predicted Functional Partners:
camsap1a
Calmodulin-regulated spectrin-associated protein 1a.
      
 0.810
nup54
Nucleoporin 54.
      
 0.807
rbm22
Pre-mRNA-splicing factor RBM22; Required for pre-mRNA splicing as component of the activated spliceosome. Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle (By similarity). Required for normal early embryogenesis.
      
 0.744
zbtb46
Zinc finger and BTB domain-containing 46.
      
 0.742
manba
Mannosidase, beta A, lysosomal.
      
 0.699
clns1a
Chloride channel, nucleotide-sensitive, 1A.
      
 0.694
faf1
Fas (TNFRSF6)-associated factor 1.
      
 0.601
pum2
Pumilio RNA-binding family member 2.
   
 
 0.601
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6; Belongs to the DEAD box helicase family.
   
 
 0.580
map3k1
Mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase.
      
 0.543
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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