Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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[Homology]
Score
mvkMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (396 aa)    
Predicted Functional Partners:
pmvk
Phosphomevalonate kinase.
   
 0.997
mvda
Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes; Belongs to the diphosphomevalonate decarboxylase family.
 
 
 0.997
hmgcra
3-hydroxy-3-methylglutaryl coenzyme A reductase.
  
 0.992
hmgcrb
3-hydroxy-3-methylglutaryl coenzyme A reductase.
  
 0.986
hmgcs1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.969
fdps
Farnesyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
  
 0.931
idi1
Isopentenyl-diphosphate delta isomerase 1.
  
 
 0.902
fdft1
Farnesyl-diphosphate farnesyltransferase 1.
   
  
 0.883
fnta
Farnesyltransferase, CAAX box, alpha.
 
    
 0.855
nsdhl
NAD(P)-dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family.
   
 0.850
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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