node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dkk1b | wif1 | ENSDARP00000066476 | ENSDARP00000019818 | Dickkopf WNT-signaling pathway inhibitor 1b. | Wnt inhibitory factor 1; Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation. | 0.853 |
dkk1b | wnt1 | ENSDARP00000066476 | ENSDARP00000072397 | Dickkopf WNT-signaling pathway inhibitor 1b. | Protein Wnt-1; Ligand for members of the frizzled family of seven transmembrane receptors. Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation (By similarity). Involved in neurogenesis. Performs a partially redundant function with wnt10b in the formation of the midbrain-hindbrain boundary (MHB) organizer. In the hindbrain, mediates lateral inhibition of boundary cell specification, probably via up-regulation of proneural and Delta gene expression in non-boundary cells; localized expression of wnt1 in boundary cells is maintained vi [...] | 0.814 |
dkk1b | wnt10a | ENSDARP00000066476 | ENSDARP00000005680 | Dickkopf WNT-signaling pathway inhibitor 1b. | Protein Wnt-10a; Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Required for normal tooth development. Regulates the expression of genes involved in tooth development. Belongs to the Wnt family. | 0.613 |
dkk1b | wnt2ba | ENSDARP00000066476 | ENSDARP00000094209 | Dickkopf WNT-signaling pathway inhibitor 1b. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.598 |
dkk1b | wnt3a | ENSDARP00000066476 | ENSDARP00000089165 | Dickkopf WNT-signaling pathway inhibitor 1b. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.900 |
dkk1b | wnt4 | ENSDARP00000066476 | ENSDARP00000095904 | Dickkopf WNT-signaling pathway inhibitor 1b. | Protein Wnt-4a; Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Plays an important role in embryonic development. | 0.649 |
dkk1b | wnt5a | ENSDARP00000066476 | ENSDARP00000137200 | Dickkopf WNT-signaling pathway inhibitor 1b. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.745 |
dkk1b | wnt5b | ENSDARP00000066476 | ENSDARP00000134193 | Dickkopf WNT-signaling pathway inhibitor 1b. | Protein Wnt-5b; Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. Required during embryogenesis for extension of the primary anterior-posterior axis. | 0.804 |
dkk1b | wnt8a | ENSDARP00000066476 | ENSDARP00000116057 | Dickkopf WNT-signaling pathway inhibitor 1b. | Protein Wnt-8a; Ligand for members of the frizzled family of seven transmembrane receptors. Plays a role in embryonic patterning. May be involved in the specification of the spatial patterns of expression of Gsc and other regulatory genes leading to the establishment of the embryonic axis; Belongs to the Wnt family. | 0.839 |
notum1b | wif1 | ENSDARP00000150237 | ENSDARP00000019818 | Inactive palmitoleoyl-protein carboxylesterase notum1b. | Wnt inhibitory factor 1; Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation. | 0.855 |
wif1 | dkk1b | ENSDARP00000019818 | ENSDARP00000066476 | Wnt inhibitory factor 1; Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation. | Dickkopf WNT-signaling pathway inhibitor 1b. | 0.853 |
wif1 | notum1b | ENSDARP00000019818 | ENSDARP00000150237 | Wnt inhibitory factor 1; Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation. | Inactive palmitoleoyl-protein carboxylesterase notum1b. | 0.855 |
wif1 | wnt1 | ENSDARP00000019818 | ENSDARP00000072397 | Wnt inhibitory factor 1; Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation. | Protein Wnt-1; Ligand for members of the frizzled family of seven transmembrane receptors. Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation (By similarity). Involved in neurogenesis. Performs a partially redundant function with wnt10b in the formation of the midbrain-hindbrain boundary (MHB) organizer. In the hindbrain, mediates lateral inhibition of boundary cell specification, probably via up-regulation of proneural and Delta gene expression in non-boundary cells; localized expression of wnt1 in boundary cells is maintained vi [...] | 0.869 |
wif1 | wnt10a | ENSDARP00000019818 | ENSDARP00000005680 | Wnt inhibitory factor 1; Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation. | Protein Wnt-10a; Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Required for normal tooth development. Regulates the expression of genes involved in tooth development. Belongs to the Wnt family. | 0.854 |
wif1 | wnt2ba | ENSDARP00000019818 | ENSDARP00000094209 | Wnt inhibitory factor 1; Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.849 |
wif1 | wnt3a | ENSDARP00000019818 | ENSDARP00000089165 | Wnt inhibitory factor 1; Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.898 |
wif1 | wnt4 | ENSDARP00000019818 | ENSDARP00000095904 | Wnt inhibitory factor 1; Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation. | Protein Wnt-4a; Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Plays an important role in embryonic development. | 0.873 |
wif1 | wnt5a | ENSDARP00000019818 | ENSDARP00000137200 | Wnt inhibitory factor 1; Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.888 |
wif1 | wnt5b | ENSDARP00000019818 | ENSDARP00000134193 | Wnt inhibitory factor 1; Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation. | Protein Wnt-5b; Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. Required during embryogenesis for extension of the primary anterior-posterior axis. | 0.894 |
wif1 | wnt8a | ENSDARP00000019818 | ENSDARP00000116057 | Wnt inhibitory factor 1; Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation. | Protein Wnt-8a; Ligand for members of the frizzled family of seven transmembrane receptors. Plays a role in embryonic patterning. May be involved in the specification of the spatial patterns of expression of Gsc and other regulatory genes leading to the establishment of the embryonic axis; Belongs to the Wnt family. | 0.854 |