STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tbr1bT-box brain transcription factor 1b. (676 aa)    
Predicted Functional Partners:
satb2
DNA-binding protein SATB.
   
  
 0.877
pax6a
Paired box protein Pax-6; Transcription factor expressed in spatially restricted regions of the neural tube during embryonic development; Belongs to the paired homeobox family.
   
 
 0.856
emx3
Empty spiracles homeobox 3.
   
  
 0.770
fezf2
Fez family zinc finger protein 2; Transcription repressor. Component of the regulatory cascade that controls the development of dopaminergic (DA) and serotonergic (5HT) neurons.
   
 
 0.761
Reln
Reelin domain-containing protein.
   
  
 0.737
foxg1a
Forkhead box G1a.
   
  
 0.730
emx1
Homeobox protein EMX1; May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system; Belongs to the EMX homeobox family.
   
  
 0.699
dyrk1aa
Dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 1A, a.
      
 0.696
dlx2a
Homeobox protein Dlx2a; Involved in the development of the inner ear; Belongs to the distal-less homeobox family.
   
 
 0.693
emx2
Empty spiracles homeobox 2.
   
  
 0.680
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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