Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
slc10a4Solute carrier family 10 member 4. (417 aa)    
Predicted Functional Partners:
tmem169a
Transmembrane protein 169a.
      
 0.792
slc10a7
Sodium/bile acid cotransporter 7; Involved in teeth and skeletal development. Has an essential role in the biosynthesis and trafficking of glycosaminoglycans and glycoproteins to produce a proper functioning extracellular matrix (By similarity). Required for extracellular matrix mineralization. Also involved in the regulation of cellular calcium homeostasis (By similarity). Does not show transport activity towards bile acids or steroid sulfates.
      
 0.779
lpar2a
Lysophosphatidic acid receptor 2a; Belongs to the G-protein coupled receptor 1 family.
      
 0.720
lpar2b
Lysophosphatidic acid receptor 2b; Belongs to the G-protein coupled receptor 1 family.
      
 0.685
slain2
SLAIN motif family, member 2.
 
    
 0.684
slc22a23
Solute carrier family 22 member 23.
   
  
 0.675
slc18b1
Solute carrier family 18 member B1.
      
 0.662
zfand1
Zinc finger, AN1-type domain 1.
      
 0.627
nr1h5
Nuclear receptor subfamily 1, group H, member 5.
   
  
 0.618
eef1e1
Eukaryotic translation elongation factor 1 epsilon 1.
      
 0.607
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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