Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
itm2baIntegral membrane protein 2Ba. (261 aa)    
Predicted Functional Partners:
appb
Amyloid beta (A4) precursor protein b.
   
 
 0.701
appa
Amyloid beta (A4) precursor protein a.
   
 
 0.701
aplp2
Amyloid beta (A4) precursor-like protein 2.
   
 
 0.670
scamp1
Secretory carrier-associated membrane protein.
    
 
 0.585
tmem59
Si:dkey-181m9.10 protein.
   
 
 0.585
tmem59l
Transmembrane protein 59-like.
   
   0.561
mlnr
Motilin receptor; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.542
cdadc1
Cytidine and dCMP deaminase domain-containing protein 1.
      
 0.539
aplp1
Amyloid beta (A4) precursor-like protein 1.
   
 
 0.526
sybl1
Synaptobrevin-like 1; Belongs to the synaptobrevin family.
      
 0.507
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.