Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ankrd45Ankyrin repeat domain 45. (224 aa)    
Predicted Functional Partners:
hsp90b1
Heat shock protein 90, beta (Grp94), member 1.
   
 0.971
hyou1
Hypoxia up-regulated protein 1; Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding; Belongs to the heat shock protein 70 family.
   
 
 0.960
dnajc10
DnaJ (Hsp40) homolog, subfamily C, member 10.
  
 0.959
sec63
SEC63 homolog, protein translocation regulator.
  
 
 0.957
hspd1
Heat shock 60kD protein 1 (Chaperonin); Belongs to the chaperonin (HSP60) family.
  
 0.898
canx
Calnexin.
   
 
 0.880
clgn
Calmegin.
   
 
 0.880
E9QJ85_DANRE
Si:ch211-274f20.2.
   
 
 0.880
sil1
SIL1 nucleotide exchange factor.
   
 0.820
hspbp1
HSPA (heat shock 70kDa)-binding protein, cytoplasmic cochaperone 1.
   
 0.820
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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